| 1775-78 Vice-Admiral James Young |
| 1778-79 Rear-Admiral Hon. Samuel Barrington |
| 1779 Vice-Admiral Hon John Byron |
| 1779-80 Rear-Admiral Sir Hyde Parker |
| 1780-81 Admiral Sir George Rodney |
| 1781-82 Rear-Admiral Sir Samuel Hood |
| 1782 Admiral Sir George Rodney |
| 1782-83 Admiral Hugh Pigot |
| 1783-86 Rear-Admiral Sir Richard Hughes |
| 1786 Commodore Sir Richard Bickerton (did not take up position) |
| 1787-90 Commodore William Parker |
| 1789-93 Rear-Admiral Sir John Laforey |
| 1793 Rear-Admiral Alan Gardner |
| 1793-94 Vice-Admiral Sir John Jervis |
| 1794-95 Vice-Admiral Benjamin Caldwell |
| 1795-96 Admiral Sir John Laforey |
| 1796 Rear-Admiral Sir Hugh Christian |
| 1796-99 Rear-Admiral Henry Harvey |
| 1799-01 Vice-Admiral Lord Hugh Seymour |
| 1800-01 Rear-Admiral John Thomas Duckworth |
| 1801-02 Rear-Admiral John Totty |
| 1802-03 Commodore Hon. Robert Stopford |
| 1802-05 Commodore Samuel Hood |
| 1805-10 Rear-Admiral Hon. Sir Alexander Cochrane |
| 1811-14 Rear-Admiral Sir Francis Laforey |
| 1814-16 Rear-Admiral Sir Philip Durham |
| 1816-19 Rear-Admiral John Harvey |
| 1818-19 Rear-Admiral Donald Campbell |
| 1819-20 Commodore Thomas Huskisson |
| 1820-21 Rear-Admiral William Fahie |
| Renamed West Indies |
| Renamed North America and West Indies Station |
| 1832-36 Vice-Admiral Sir George Cockburn |
| 1836-37 Vice-Admiral Sir Peter Halkett |
| 1837-39 Vice-Admiral Sir Charles Paget |
| 1839-41 Vice-Admiral Sir Thomas Harvey |
| 1841-44 Vice-Admiral Sir Charles Adam |
| 1844-48 Vice-Admiral Sir Francis Austen |
| 1848-51 Vice-Admiral Earl Dundonald |
| 1851-53 Vice-Admiral Sir George Francis Seymour |